Missouri Breaks Industries Research Inc. is a small Indian-owned management firm located on the Cheyenne River Sioux Reservation in South Dakota. It is centrally located and primarily works and employs people from a Federal Labor Surplus area - specifically the Federal Indian Reservations of North and South Dakota. Missouri Breaks industries is qualified under 48 CFR 3-380.5 as a "Buy Indian" business to conduct research of medical problems and to disseminate information learned through its research to healthcare providers, tribal leaders, and community members.